[すべて] [A01の成果] [A02の成果] [A03の成果] 

  1. Kawagoe. R.; Takashima. I.; Uchinomiya. S.; Ojida*. A., Reversible Ratiometric Detection of Highly Reactive Hydropersulfides Using a FRET-Based Dual Emission Fluorescent Probe, Chemical Science, 2017, 8, 1134-1140 DOI: 10.1039/c6sc03856e. Tags: 王子田 A01
  2. Wongkongkatep. J.; Ojida. A.; Hamachi. I., Fluorescence Sensing of Inorganic Phosphate and Pyrophosphate Using Small Molecular Sensors and Their Applications, Topics in Current Chemistry, 2017, 375:30 DOI: 10.1007/s41061-017-0120-0 Tags: 王子田 A01
  3. Kurashige. N.; Fuchida. H.; Tabata. S.; Uchinomiya. S.; Ojida*. A., Discovery of highly reactive peptide tag by ELISA-type screening for specific cysteine conjugation, Bioorganic & Medicinal Chemistry Letters, 2017, 27,3486-3489  DOI: 10.1016/j.bmcl.2017.05.069 Tags: 王子田 A01
  4. Delsuc*. N.; Uchinomiya. S.; Ojida. A.; Hamachi. I, A host–guest system based on collagen-like triple-helix hybridization, Chemical Communications2017, 53, 6856-6859  DOI :10.1039/C7CC03055J Tags: 王子田 A01
  5. Wu. Q.; Yasui. T.; Rahong. S.; Yanagida. T.; Kanai. M.; Nagashima. K.; Tokeshi. M.; Kawai. T.; Baba. Y., A millisecond micro-RNA separation technique by a hybrid structure of nanopillars and nanoslits, Scientific Reports, 2017, 7, 43877. DOI:10.1038/srep43877 Tags: 馬場 A03
  6. Doi. R.; Tsuchiya. T.; Mitsutake. N.; Nishimura. S.; Matsuu-Matsuyama. M.; Nakazawa. Y.; Ogi. T.;  Akita. S.; Yukawa. H.; Baba. Y.; Yamasaki. N.; Matsumoto. K.; Miyazaki. T.; Kamohara. R.; Hatachi. G.; Sengyoku. H.; Watanabe. H.; Obata. T.; E. Niklason. L.; Nagayasu. T., Transplantation of bioengineered rat lungs recellularized with endothelial and adipose-derived stromal cells, Scientific Reports, 7, 2017, Article number: 8447 DOI:10.1038/s41598-017-09115-2 Tags: 馬場 A03
  7. Yasaki. H.; Yasui. T.; Yanagida. T.; Kaji. N.; Kanai. M.; Nagashima. K.; Kawai. T.; Baba. Y., Substantial Expansion of Detectable Size Range in Ionic Current Sensing through Pores by Using a Microfluidic Bridge Circuit, J. Am. Chem. Soc., 2017, 139 (40), 14137-14142. DOI: 10.1021/jacs.7b06440 Tags: 馬場 A03
  8. Yasui. T,; Yanagida. T.; Ito. S.; Konakade. Y.; Takeshita. D.; Naganawa. T.; Nagashima. K.;  Shimada. T.; Kaji. N.; Nakamura. Y.; A. Thiodorus. I.; He. Y.; Rahong. S.; Kanai. M.; Yukawa. H.; Ochiya. T.; Kawai. T.; Baba. Y., Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires, Science Advances, 2017, 3,12, e1701133. DOI:10.1126/sciadv.1701133 Tags: 馬場 A03
  9. Takahashi. S.; A. Brazier. J.; Sugimoto. N., Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase, Proc. Natl. Acad. Sci. U. S. A., 2017, 114, 9605-9610 DOI: 10.1073/pnas.1704258114 Tags: 杉本 A02
  10. Tateishi-Karimata. H.; Kawauchi. K.; Sugimoto. N.,Destabilization of DNA G-quadruplexes by chemical environment changes during tumor progression facilitates transcription, J. Am. Chem. Soc, 2018, 140 (2), pp 642–651 DOI: 10.1021/jacs.7b09449 Tags: 杉本 A02
  11. Shigemitsu. H.; Fujisaku. T.; Tanaka. W.; Kubota. R.; Minami. S.; Urayama. K.; Hamachi, I.*, An adaptive supramolecular hydrogel comprising self-sorting double nanofibre networks, Nature Nanotechnology, 2018, 13, 165-175 DOI:10.1038/s41565-017-0026-6 Tags: 浜地 A01
  12. Teng. Y.; Pramanik. S.; Tateishi-Karimata. H.; Ohyama. T.; Sugimoto. N., Drastic stability change of X-X mismatch in d(CXG) trinucleotide repeatdisorders under molecular crowding condition, Biochem, Biophys. Res. Commun, 2018, 496( 2 ), 601 -607 DOI: 10.1016/j.bbrc.2018.01.083 Tags: 杉本 A02
  13. Sakurai. K.; Yagi. M.; Konuma. T.; Takahashi. S.; Nishimura. C.; Goto. Y., Non-Native alpha-Helices in the Initial Folding Intermediate Facilitate the Ordered Assembly of the beta-Barrel in beta-Lactoglobulin, Biochemistry, 2017, 56 (36), 4799-4807. DOI: 10.1021/acs.biochem.7b00458 Tags: 後藤 A02
  14. Matsushita. Y.; Sekiguchi. H.; Chang. J. W.; Nishijima. M.; Ikezaki. K.; Hamada. D.; Goto. Y.; Sasaki. Y.C., Nanoscale dynamics of protein assembly networks in supersaturated solutions, Scientific Reports, 2017, 7, 13883. DOI: 10.1038/s41598-017-14022-7 Tags: 後藤 A02
  15. Nitani. A.; Muta. H.; Adachi. M.; So. M.; Sasahara. K.; Sakurai. K.; Chatani. E.; Naoe. K.; Ogi. H.; Hall. D.; Goto. Y., Heparin-dependent aggregation of hen egg white lysozyme reveals two distinct mechanisms of amyloid fibrillation, J. Biol. Chem., 2017, 292 (52), 21219-21230. DOI: 10.1074/jbc.M117.813097 Tags: 後藤 A02
  16. Ziadi. A.; Uchida. N.; Kato. H.; Hisamatsu. R.; Sato, A.; Hagihara. S.; Itami. K.; Torii. K.U., Discovery of Synthetic Small Molecules that Enhance the Number of Stomata: C-H Functionalization Chemistry for Plant Biology, Chem. Commun., 2017, 53, 9632-9635. DOI:10.1039/C7CC04526C Tag: 萩原 A01
  17. Amaike. K.; Tamura. T.; Hamachi*. I., Recognition-driven chemical labeling of endogenous proteins in multi-molecular crowding live cells, Chemical Communications, Feature Article, 2017, 53, 11972-11983 DOI: 10.1039/c7cc07177a. Tags: 浜地 A01
  18. Tamura. T.; Song. Z.; Amaike. K.; Lee. S.; Yin. S.; Kiyonaka. S.; Hamachi*. I., Affinity-guided Oxime Chemistry for Selective Protein Acylation in Live Tissue Systems, Journal of the American Chemical Society, 2017, 139(40), 14181-14191 DOI: 10.1021/jacs.7b07339. Tags: 浜地 A01
  19. Matsuo. K.; Nishikawa. Y.; Masuda. M.; Hamachi*. I., Live-cell Protein Sulfonylation Based on Proximity-driven N-Sulfonyl Pyridone Chemistry, Angewandte Chemie International Edition, 2018, 15, 659-662 DOI: 10.1002/anie.201707972. Tags: 浜地 A01
  20. Matsunaga. S.; Hano, Y.;  Saito. Y.; Fujimoto. K.J.; Kumasaka. T.; Matsumoto. S.; Kataoka. T.; Shima. F.; Tanaka. S., Structural Transition of Solvated H-Ras/GTP Revealed by Molecular Dynamics Simulation and Local Network Entropy, J. Mol. Graph. Model. 77 (2017) 51-63. DOI: 10.1016/j.jmgm.2017.07.028 Tags: 田中 A02
  21. Tanaka. S., Information Geometrical Characterization of the Onsager-Machlup Process, Chem. Phys. Lett. 689 (2017) 152-155. DOI: 10.1016/j.cplett.2017.10.005  Tags: 田中 A02
  22. Uchida. N.; Takahashi. K.; Iwasaki. R.; Yamada. R.; Yoshimura. M.; Endo. T. A. ; Kimura. S.; Zhang, H.; Nomoto. M.; Tada. Y.; Kinoshita. T.; Itami. K.; Hagihara. S.;  Torii. K. U., Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair, Nat. Chem. Biol., 2018, 14, 299-305, DOI: 10.1038/nchembio.2555. Tags: 萩原 A01
  23. Yoshimura. M.; Sato. A.; Kuwata. K.; Inukai. Y.; Kinoshita. T.; Itami. K.; Tsuchiya. Y.; Hagihara. S., Discovery of shoot branching regulator targeting strigolactone re-ceptor DWARF14, ACS Central Science, Article ASAP, DOI: 10.1021/acscentsci.7b00554 Tags: 萩原 A01
  24. Shigemitsu, H.; Fujisaku, T.; Tanaka, W.; Kubota, R.; Minami, S.; Urayama, K.; Hamachi, I.*, An adaptive supramolecular hydrogel comprising self-sorting double nanofibre networks, Nature Nanotechnology, 2018, 13, 165-175 DOI:10.1038/s41565-017-0026-6
    Tags: 浜地 A01
  25. Ueda. T.; Tamura. T.; Hamachi. I., In situ Construction of Protein-based Semisynthetic Biosensors, ACS Sensors, 2018, 3 ( 3 ) 527 – 539  DOI :10.1021/acssensors.7b00894 Tags: 浜地 A01
  26. Kiyonaka. S.*; Sakamoto. S.; Wakayama. S.; Morikawa. Y.; Tsujikawa. M.; Hamachi. I.*, Ligand-directed chemistry of AMPA receptors confers live-cell fluorescent biosensors, ACS Chemical Biology,  2018,13 (7), 1880–1889 DOI : 10.1021/acschembio.7b01042 Tags: 浜地 A01
  27. Sato. N.; Takahashi. S.; Tateishi-Karimata. H.; Hazemi.E. M.; Chikuni. T.; Onizuka. K.; Sugimoto. N.,Alkylating Probes for G-Quadruplex Structure and Evaluation of the Properties of the Alkylated G-Quadruplex DNA Org. Biomol. Chem.,2018, 16,1436-1441 DOI:10.1039/C7OB03179C Tags: 杉本A02
  28. Natan. E.; Endoh. T.; Haim-Vilmovsky. L.; Flock. T.; Chalancon. G.; Hopper. J. T. S.; Kintses. B.; Horvath. P.; Daruka.L.; Fekete. G.; Pál. C.; Papp. B.; Oszi.E.; Magyar. Z.; Marsh. J.A.; Elcock. A.H.; Babu. M.N.; Robinson.C.V.; Sugimoto. N.; Teichmann. S.A., Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins, Nat Struct Mol Biol.,2018, 25, 279-288, DOI:10.1038/s41594-018-0029-5. Tags: 杉本 A02
  29. Trajkovsk. M.; Endoh. T.; Tateishi-Karimata. H.; Ohyama. T.; Tanaka. S.; Plavec. J.; Sugimoto. N., Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations, Nucleic Acids Res., 2018, 46, 8, 4301–4315, DOI:10.1093/nar/gky250 Tags: 杉本A02
  30. Usui. K.; Okada. A.; Sakashita. S.; Shimooka. M.; Tsuruoka. T.; Nakano. S.; Miyoshi. D.; Mashima. T.; Katahira. M.; Hamada. Y., DNA G-Wire Formation Using an Artificial Peptide is Controlled by Protease Activity, Molecules, 2017, 22, 1991 DOI:10.3390/molecules22111991. Tags: 杉本 A02
  31. Y. Teng, S. Pramanik, H. Tateishi-Karimata, T. Ohyama, and N. Sugimoto, Drastic stability change of X-X mismatch in d(CXG) trinucleotide repeat disorders under molecular crowding condition, Biochem. Biophys. Res. Commun., 2018, 496, 2, 642-651
    Tags: 杉本A02
  32. Takahashi. S.; Kim T. K.; Podbevsek. P.; Plavec. J.; Kim H. B.; Sugimoto. N., Recovery of the formation and function of oxidized G-quadruplexes by a pyrene-modified guanine-tract, J. Am. Chem. Soc., 2018, 140, (17), 5774-5783, DOI:10.1021/jacs.8b01577                                           Tags: 杉本A02
  33. Rode AB.; Endoh. T.; Sugimoto. N., Crowding Shifts the FMN Recognition Mechanism of Riboswitch Aptamer from Conformational Selection to Induced Fit, Angew. Chem. Int. Ed., 2018, 57, (23), 6868-6872  DOI: 10.1002/anie.201803052                                                                                                           Tags: 杉本A02
  34. Takaoka. Y.; Uchinomiya. S.; Kobayashi. D.; Endo. M.; Hayashi. T.; Fukuyama. Y.; Hayasaka. H.; Miyasaka. M.; Ueda. T.; Shimada. I.; Hamachi. I., Endogenous Membrane Receptors Labeling by Reactive Cytokines/Growth Factors to Chase Their Dynamics in Live Cells, Chem, 2018, 4, 1451-1464 Doi.org/10.1016/j.chempr.2018.03.021 Tags: 浜地 A01
  35. Hostachy. S.; Masuda. M.; Miki, T.; Hamachi. I.; Sagan. S.; Lequin. O.; Medjoubi. K.; Somogyi. A.; Delsuc*. N.; Policar* C., Graftable SCoMPIs Enable The Labeling and X-Ray Fluorescence Imaging of Proteins, Chemical Science, 2018, 9, 4483-4487 (2018) DOI:10.1039/c8sc00886h Tags: 浜地 A01
  36. Tamura. T.; Ueda. T.; Goto. T.; Tsukidate. T.; Shapira. Y.; Nishikawa. Y.; Fujisawa. A.; Hamachi*. I., Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide, Nature Communications, 2018, 9, 1870, DOI:10.1038/s41467-018-04343-0 Tags: 浜地 A01
  37. Kubota, R.; Liu, S.; Shigemitsu, H.; Nakamura, K.; Tanaka, W.; Ikeda, M.; Hamachi, I., Imaging-Based Study on Control Factors over Self-Sorting of Supramolecular Nanofibers Formed from Peptide- and Lipid-Type Hydrogelators, Bioconjugate Chemistry, 2018, Jun 20;29(6):2058-2067. DOI:10.1021/acs.bioconjchem.8b00260 Tags: 浜地 A01
  38. Meguro, T.; Terashima, N.; Ito, H.; Koike, Y.; Kii, I.; Yoshida, S.; Hosoya, T., Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells, Chem Commun, 2018, 54, 7904-7907 DOI: 10.1039/c8cc00179k. Tags: 喜井 A02
  39. Matsumoto. G.; Inobe. T.; Amano, T.; Murai. K.; Nukina. N.; Mori. N., N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression, Scientific Reports, 2018, 8, 9585 DOI: 10.1038/s41598-018-27872-6 Tags: 伊野部 A01
  40. Inobe. T.; Tsukamoto. M.; Nozaki. M., Proteasome-mediated protein degradation is enhanced by fusion ubiquitin with unstructured degron., Biochem. Biophys. Res. Commun., 2018, 501, 948-954 DOI: 10.1016/j.bbrc.2018.05.088 Tags: 伊野部 A01
  41. Saikusa. K.; Osakabe. A.; Kato. D.; Fuchigami. S.; Nagadoi. A.; Nishimura. Y.; Kurumizaka. H.; Akashi. S., Structural Diversity of Nucleosomes Characterized  by Native Mass Spectrometry, Anal. Chem., 2018, 90, 8217-8226 Doi: 10.1021/acs.analchem.8b01649 Tags: 明石 A02
  42. Yamatsugu, K.; Furuta, M.; Xi, S.; Amamoto, Y.; Liu, J.; Kawashima, S. A.; Kanai, M., Kinetic Analyses and Structure-Activity Relationship Studies of Synthetic Lysine Acetylation Catalysts, Bioorg. Med. Chem, 2018, Volume 26, Issue 19, 15 , Pages 5359-5367, DOI: 10.1016/j.bmc.2018.07.009 Tags: 山次 A01
  43. Sato. S.; Hatano. K.; Tsushima. M.; Nakamura. H., 1-Methyl-4-aryl-urazole (MAUra) Labels Tyrosine in Proximity to Ruthenium Photocatalyst., Chem. Commun. 2018, 54, 5871-5874.  DOI: 10.1016/j.bmc.2018.05.002 Tags: 中村 A01
  44. Ueda, H.; Yoshimori, A.; Nakamura, H., Discovery of bicycle[3,3,1]non-2-ene as a novel skeleton for HIF-1 inhibitors, Bioorg. Med. Chem, 2018,26(12):3345-3351DOI: 10.1016/j.bmc.2018.05.002 Tags: 中村 A01
  45. Akazawa. T.; Uchida. Y.; Miyauchi. E.; Tachikawa. M.; Ohtsuki. S.; Terasaki. T., High Expression of UGT1A1/1A6 in Monkey Small Intestine: Comparison of Protein Expression Levels of Cytochromes P450, UDP-Glucuronosyltransferases, and Transporters in Small Intestine of Cynomolgus Monkey and Human. Mol Pharm., 2018, 15(1), 127-140. DOI: 10.1021/acs.molpharmaceut.7b00772.  Tags: 内田 A03
  46. Sasaki. K.; Tachikawa. M.; Uchida. Y.; Hirano. S.; Kadowaki. F.; Watanabe. M.; Ohtsuki. S.; Terasaki. T., ATP-binding cassette transporter A subfamily 8 is a sinusoidal efflux transporter for cholesterol and taurocholate in mouse and human liver, Mol Pharm., 2018, 15(2), 343-355. DOI: 10.1021/acs.molpharmaceut.7b00679. Tags: 内田 A03
  47. Zhang. Z.; Tachikawa. M.; Uchida. Y.; Terasaki. T., Drug clearance from cerebrospinal fluid mediated by organic anion transporters 1 (Slc22a6) and 3 (Slc22a8) at arachnoid membrane of rats. Mol Pharm., 2018, 15(3), 911-922. DOI: 10.1021/acs.molpharmaceut.7b00852. Tags: 内田 A03
  48. Miyauchi. E.; Furuta. T.; Ohtsuki. S.; Tachikawa. M.; Uchida. Y.; Sabit, H.; Obuchi, W.; Baba, T.; Watanabe, M.; Terasaki, T.; Nakada, M., Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics. PLOS ONE, 2018, 13(3), e0193799. DOI: 10.1371/journal.pone.0193799. Tags: 内田 A03
  49. Tachikawa. M.; Sumiyoshiya. Y.; Saigusa. D.; Sasaki. K.; Watanabe. M.; Uchida. Y.; Terasaki, T., Liver zonation index of drug transporter and metabolizing enzyme protein expressions in mouse liver acinus. Drug Metab Dispos., 2018, 46(5), 610-618. DOI: 10.1124/dmd.117.079244. Tags: 内田 A03
  50. Hiroshima. Y.; Yamamoto. T.; Watanabe. M.; Baba. Y.; Shinohara. Y., Effects of cold exposure on metabolites in brown adipose tissue of rats, Molecular Genetics and Metabolism Reports, 2018, 15, 36-42. Open Access DOI: 10.1016/j.ymgmr.2018.01.005 Tags: 馬場 A03
  51. Pillai. S. S.; Yukawa. H.; Onoshima. D.; Biju. V.; Baba. Y., Quantum dot-peptide nanoassembly on mesoporous silica nanoparticle for biosensing Nano Hybrids and Composites, 2018, Vol. 19, 55-72, DOI: 10.4028/www.scientific.net/NHC.19.55  Tags: 馬場 A03
  52. Watanabe. H.; Tsuchiya. T.; Shimoyama. K.; Shimizu. A.; Akita. S.; Yukawa. H.; Baba. Y.; Nagayasu. T., Adipose-derived mesenchymal stem cells attenuate rejection in a rat lung transplantation model, Journal of Surgical Research, 2018, 227, 17-27 DOI: 10.1016/j.jss.2018.01.016 Tags: 馬場 A03
  53. Yukawa. H.; Suzuki. K.; Aoki. K.; Arimoto. T.; Yasui. T.; Kaji. N.; Ishikawa. T.; Ochiya. T.; Baba. Y., Imaging of angiogenesis of human umbilical vein endothelial cells by uptake of exosomes secreted from hepatocellular carcinoma cells, Scientific Reports, 2018,  8,  6765 DOI: 10.1038/s41598-018-24563-0 Tags: 馬場 A03
  54. Okumura, H.; Nanizawa, E.; Nakanishi, A.; Yukawa, H.; Hashita, T.; Iwao, T.; Baba, Y.; Ishikawa, T.; Matsunaga*, T., Effective Transplantation of Two- and Three-Dimensional Cultured Hepatocyte Spheroids Confirmed by Quantum Dot Imaging, Adv. Biosystems, 2018, 2, 1800137 DOI:10.1002/adbi.201800137 Tags: 馬場 A03
  55. Yamada. R.; Murai. K.; Uchida. N.; Takahashi. K.; Iwasaki. R.; Tada. Y.; Kinoshita. T.; Itami. K.; Torii. U. K.; Hagihara. S., A super strong engineered auxin-TIR1 pair, Plant and Cell Physiology, 2018, 59(8):1538-1544, DOI:10.1093/pcp/pcy127 Tags: 萩原 A01
  56. Fendrych. M.; Akhmanova. M.; Merrin. J.; Glanc. M.; Hagihara. S.; Takahashi. K.; Uchida. N.; Torii. U. K.; Friml. J., Rapid and reversible root growth inhibition by TIR1 auxin signalling, Nat. Plants., 2018, 4, 453-459. DOI: 10.1038/s41477-018-0190-1 Tags: 萩原 A01
  57. Hayashi. T.; Matsuda. T.; Nagata. T.; Katahira. M.; Kinoshita. M., Mechanism of protein-RNA recognition: Analysis based on statistical mechanics of hydration, Physical Chemistry Chemical Physics, 2018, 20, 9167-9180, DOI: 10.1039/C8CP00155C Tags: 片平 A02
  58. Nishimura. H.; Kamiya. A.; Nagata. T.; Katahira. M.; Watanabe. T., Direct evidence for α ether linkage between lignin and carbohydrates in wood cell walls, Scientific Reports, 2018, 8, 6538, DOI: 10.1038/s41598-018-24328-9 Tags: 片平 A02
  59. Kitada. A.; Kintsu. K.; Takeoka. S.; Fukami. K.; Saimura. M.; Nagata. T.; Katahira. M.; Murase. K., A Hydronium Solvate Ionic Liquid: Ligand Exchange Conduction Driven by Labile Solvation, Journal of the Electrochemical Society, 2018, 165, H496-H499 Tags: 片平 A02
  60. Kawasaki. Y.; Kurosaki. K.; Kan. D.; Borges. K. I.; Satake. A.; Sato. M.; Kondo. K.;  Katahira. M.; Suzuki. I.; Takeda. M., Identification and characterization of the S-layer formed on the sheath of Thiothrix nivea, Archives of Microbiology, 2018Volume 200, Issue 8, 1257–1265, DOI: 10.1007/s00203-018-1543-x Tags: 片平 A02
  61. Osman. W. H. W.; Lin. M.I.; Kondo. K.; Nagata. T.; Katahira. M., Characterization of the glutathione S-transferases that belong to the GSTFuA class in Ceriporiopsis subvermispora: Implications in intracellular detoxification and metabolism of wood-derived compounds, Internatiomal Journal of Biological Macromolecules, 2018, 113, 1158-1166, DOI: 10.1016/j.ijbiomac.2018.03.029 Tags: 片平 A02
  62. Lin. M.I.; Nagata. T.; Katahira. M., High yield production of fungal manganase peroxidases by E. coli through soluble expression, Protein Expression and Purification, 2018, 145, 45-52, DOI: 10.1016/j.pep.2017.12.012 Tags: 片平 A02
  63. Takeda. M.; Kondo. K.; Sanda. S.; Kan. D.; Borges. K. I.; Suzuki. I.; Katahira. M., Enzymatic degradation of β-1,4-linked N-acetylglucosaminoglucan prepared from Thiothrix nivea, Internatiomal Journal of Biological Macromolecules, 2018, 109, 323-328, DOI: 10.1016/j.ijbiomac.2017.12.065 Tags: 片平 A02
  64. Watanabe. C.; Watanabe. H.; Fukuzawa. K.; Parker. L.; Okiyama. Y.; Yuki. H.;  Yokoyama. S.; Nakano. H.; Tanaka. S.; Honma. T., Theoretical Analysis of Activity Cliffs among Benzofuranone Class Pim1 Inhibitors Using the Fragment Molecular Orbital Method with Molecular Mechanics Poisson-Boltzmann Surface Area (FMO+MM-PBSA) Approach, J. Chem. Inf. Model. 57 (2017) 2996-3010. DOI: 10.1021/acs.jcim.7b00110 Tags: 田中 A02
  65. Okiyama. Y.; Nakano. T.; Watanabe. C.; Fukuzawa. K.; Mochizuki. Y.; Tanaka. S., Fragment Molecular Orbital Calculations with Implicit Solvent Based on the Poisson–Boltzmann Equation: Implementation and DNA Study, J. Phys. Chem. B 122 (2018) 4457-4471. http://dx.doi.org/10.1021/acs.jpcb.8b01172  Tags: 田中 A02
  66. Xu. F.; Tanaka. S.; Watanabe. H.; Shimane. Y.; Iwasawa. M.; Ohishi. K.; Maruyama. T., Computational Analysis of the Interaction Energies between Amino Acid Residues of the Measles Virus Hemagglutinin and Its Receptors, Viruses 10 (2018) 236 (18 pages). doi: 10.3390/v10050236 Tags: 田中 A02
  67. Maruyama. K.; Sheng. Y.; Watanabe. H.; Fukuzawa. K.; Tanaka. S., Application of Singular Value Decomposition to the Inter-Fragment Interaction Energy Analysis for Ligand Screening, Comput. Theor. Chem. 1132 (2018) 23-34. https://doi.org/10.1016/j.comptc.2018.04.001 Tags: 田中 A02
  68. Zeid. A. M.; Kaji. N.; Nasr. J. J. M.; Belal. F.; Walash. M. I.; Baba. Y., Determination of baclofen and vigabatrin by microchip electrophoresis with fluorescence detection: application of field-enhanced sample stacking and dynamic pH junction. New J. Chem. 2018, 42, 9965-9974 DOI: 10.1039/c8nj00829a Tags: 加地 A03
  69. Sano. M.; Kaji. N.; Wu. Q.; Naito. T.; Yasui. T.; Taniguchi. M.; Kawai. T.; Baba. Y., Quantitative Evaluation of Dielectric Breakdown of Silicon Micro- and Nanofluidic Devices for Electrophoretic Transport of a Single DNA Molecule. Micromachines-Basel 2018, 9, 180 DOI: 10.3390/mi9040180 Tags: 加地 A03
  70. Uchihashi. T.; Watanabe. YH.; Nakazaki. Y.; Yamasaki. T.; Watanabe. T.; Maruno. T.; Ishii. K.; Uchiyama. S.; Song. C.; Murata. K.; Iino. R.; Ando. T., Dynamic structural states of ClpB involved in its disaggregation function. Nature Communications 2018, 9, 2147. https://doi.org/10.1038/s41467-018-04587-w Tags: 内山 A03
  71. Kashida. H.; Hattori. Y.; Tazoe. K.; Inoue. T.; Nishikawa. K.; Ishii. K.; Uchiyama. S.; Yamashita. H.; Abe. M.; Kamiya. Y.; Asanuma. H., Bifacial nucleobases for hexaplex formation in aqueous solution. J. Am. Chem. Soc. 2018, 140(27): 8456-8462. doi: 10.1021/jacs.8b02807 Tags: 内山 A03
  72. Terakawa. S. M.; Lee. Y.-H.; Kinoshita. M.; Lin. Y.; Sugiki. T.; Fukui. N.; Ikenoue. T.; Kawata. Y.; Goto. Y., Membrane-induced Initial Structure of α-Synuclein Control its Amyloidogenesis on Model Membranes., Biochim. Biochem. Acta, 2018, 1860 (3), 757-766. DOI: 10.1016/j.bbamem.2017.12.011 Tags: 後藤 A02
  73. Goto. Y.; Adachi. M.; Muta. H.; So. M., Salt-induced Formations of Partially Folded Intermediates and Amyloid Fibrils Suggests a Common Underlying Mechanism., Biophys. Rev., 2018, 10 (2), 493-502. DOI: 10.1007/s12551-017-0370-7 Tags: 後藤 A02
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  81. Shimada, I.; Ueda, T.; Kofuku, Y.; Eddy, M.T.;  Wüthrich, K.   GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures. Nature Reviews Drug Discovery. 2018, DOI: 38/nrd.2018.180.   Tags: 上田 A02
  82. Uchida Y.; Sumiya T.; Tachikawa M.; Yamakawa T.; Murata S.; Yagi Y.; Sato K.; Stephan A.; Ito K.; Ohtsuki S.; Couraud PO.; Suzuki T.; Terasaki T., Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis. Mol Neurobiol. 2018, vol.56, Issue3, 2039-2056
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  83. Sano Y.; Mizuno T.; Mochizuki T.; Uchida Y.; Umetsu M.; Terasaki T.; Kusuhara H., Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier. Drug Metab Dispos.2018,46(11), 1767-1775. DOI: 10.1124/dmd.118.081877 Tags: 内田 A03
  84. Kuroda H.; Tachikawa M.; Yagi Y.; Umetsu M.; Nurdin A.; Miyauchi E.; Watanabe M.; Uchida Y.; Terasaki T., Cluster of Differentiation 46 is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28). Mol Pharm. 2018 16 (1), pp 292–304
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  85. Sato K.; Tachikawa M.; Watanabe M.; Miyauchi E.; Uchida Y.; Terasaki T., Identification of blood-brain barrier-permeable proteins derived from peripheral organ: In vivo and in vitro evidence of blood-to-brain transport of creatine kinase. Mol Pharm. 2019, 16 (1), pp 247–257
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  86. Narita Y Arakawa Y Yamasaki F Nishikawa R Aoki T Kanamori M Nagane M Kumabe T Hirose Y Ichikawa T Kobayashi H Fujimaki T Goto H Takeshima H Ueba T Abe H Tamiya T Sonoda Y Natsume A Kakuma T Sugita Y Komatsu N Yamada A Sasada T Matsueda S Shichijo S Itoh K Terasaki M, A randomized, double-blind, phase III trial of personalized peptide vaccination for recurrent glioblastoma, Neuro Oncol, 2018 Tags: 夏目 A03
  87. Wee CW Kim IH Park CK Kim JW Dho YS Ohka F Aoki K Motomura K Natsume A Kim N Suh CO Chang JH Kim SH Cho WK Lim DH Nam DH Choi JW Kim IA Kim CY Oh YT Cho O Chung WK Kim SH Kim E, Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study, Radiother Oncol, 129, 347-51, 2018 
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  88. Murakami T Nakazawa T Natsume A Nishimura F Nakamura M Matsuda R Omoto K Tanaka Y Shida Y Park YS Motoyama Y Nakagawa I Yamada S Tamura K Takeshima Y Takamura Y Wakabayashi T Nakase H, Novel Human NK Cell Line Carrying CAR Targeting EGFRvIII Induces Antitumor Effects in Glioblastoma Cells, Anticancer Res, 38, 5049-56, 2018 
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  89. Motomura K Sumita K Chalise L Nishikawa T Tanahashi K Ohka F Aoki K Hirano M Nakamura T Matsushita T Wakabayashi T Natsume A, Characterization of Intraoperative Motor Evoked Potential Monitoring for Surgery of the Pediatric Population with Brain Tumors, World Neurosurg, 119, e1052-e9, 2018 
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  90. Motomura K Chalise L Ohka F Aoki K Tanahashi K Hirano M Nishikawa T Wakabayashi T Natsume A, Supratotal Resection of Diffuse Frontal Lower Grade Gliomas with Awake Brain Mapping, Preserving Motor, Language, and Neurocognitive Functions, World Neurosurg, 119, 30-9, 2018  
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  91. Furuta H Yoshida T Natsume A Hida T Yatabe Y, Inflammation Flare and Radiation Necrosis Around a Stereotactic Radiotherapy-Pretreated Brain Metastasis Site After Nivolumab Treatment, J Thorac Oncol, 13, 1975-8, 2018  
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  92. Iwami K Natsume A Wakabayashi T, Cytokine Therapy of Gliomas, Prog Neurol Surg, 32, 79-89, 2018  
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  93. Yamaguchi J Kato S Iwata E Aoki K Kabeya R Natsume A Wakabayashi T, Pediatric-Type Follicular Lymphoma in the Dura: A Case Report and Literature Review, World Neurosurg, 115, 176-80, 2018
    9. Choo J Takeuchi K Nagata Y Ohka F Kishida Y Watanabe T Satoh Y Nagatani T Kato K Wakabayashi T Natsume A, Neuroendoscopic Cylinder Surgery and 5-Aminolevulinic Acid Photodynamic Diagnosis of Deep-Seated Intracranial Lesions, World Neurosurg, 116, e35-e41, 2018  
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  94. Krishnan H Rayes J Miyashita T Ishii G Retzbach EP Sheehan SA Takemoto A Chang YW Yoneda K Asai J Jensen L Chalise L Natsume A Goldberg GS, Podoplanin: An emerging cancer biomarker and therapeutic target, Cancer Sci, 109, 1292-9, 2018  Tags: 夏目 A03
  95. Wakabayashi T Natsume A Mizusawa J Katayama H Fukuda H Sumi M Nishikawa R Narita Y Muragaki Y Maruyama T Ito T Beppu T Nakamura H Kayama T Sato S Nagane M Mishima K Nakasu Y Kurisu K Yamasaki F Sugiyama K Onishi T Iwadate Y Terasaki M Kobayashi H Matsumura A Ishikawa E Sasaki H Mukasa A Matsuo T Hirano H Kumabe T Shinoura N Hashimoto N Aoki T Asai A Abe T Yoshino A Arakawa Y Asano K Yoshimoto K Shibui S Members of Japan Clinical Oncology Group Brain Tumor Study G, JCOG0911 INTEGRA study: a randomized screening phase II trial of interferonbeta plus temozolomide in comparison with temozolomide alone for newly diagnosed glioblastoma, J Neurooncol, 138, 627-36, 2018  
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  96. Yamamichi A Ohka F Aoki K Suzuki H Kato A Hirano M Motomura K Tanahashi K Chalise L Maeda S Wakabayashi T Kato Y Natsume A, Immunohistochemical ATRX expression is not a surrogate for 1p19q codeletion, Brain Tumor Pathol, 35, 106-13, 2018  
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  97. Hirano M Ohka F Maeda S Chalise L Yamamichi A Aoki K Kato A Tanahashi K Motomura K Nishimura Y Hara M Shinjo K Kondo Y Wakabayashi T Natsume A, A novel high-sensitivity assay to detect a small fraction of mutant IDH1 using droplet digital PCR, Brain Tumor Pathol, 35, 97-105, 2018  
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  98. Komuro A Raja E Iwata C Soda M Isogaya K Yuki K Ino Y Morikawa M Todo T Aburatani H Suzuki H Ranjit M Natsume A Mukasa A Saito N Okada H Mano H Miyazono K Koinuma D, Identification of a novel fusion gene HMGA2-EGFR in glioblastoma, Int J Cancer, 142, 1627-39, 2018  
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  99. Aoki K Nakamura H Suzuki H Matsuo K Kataoka K Shimamura T Motomura K Ohka F Shiina S Yamamoto T Nagata Y Yoshizato T Mizoguchi M Abe T Momii Y Muragaki Y Watanabe R Ito I Sanada M Yajima H Morita N Takeuchi I Miyano S Wakabayashi T Ogawa S Natsume A, Prognostic relevance of genetic alterations in diffuse lower-grade gliomas, Neuro Oncol, 20, 66-77, 2018  
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