分子夾雑の生命化学

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Original papers A01 Group

[すべて]　[A01の成果]　[A02の成果]　[A03の成果]　

  1. Kawagoe, R.; Takashima, I.; Uchinomiya, S.; Ojida*, A., Reversible Ratiometric Detection of Highly Reactive Hydropersulfides Using a FRET-Based Dual Emission Fluorescent Probe, Chemical Science, 2017, 8, 1134-1140 DOI: 10.1039/c6sc03856e.
    Tags: 王子田 A01
  2. Wongkongkatep, J.; Ojida, A.; Hamachi, I., Fluorescence Sensing of Inorganic Phosphate and Pyrophosphate Using Small Molecular Sensors and Their Applications, Topics in Current Chemistry, 2017, 375:30 DOI: 10.1007/s41061-017-0120-0
    Tags: 王子田 A01　
  3. Kurashige, N.; Fuchida, H.; Tabata, S.; Uchinomiya, S.; Ojida* A., Discovery of highly reactive peptide tag by ELISA-type screening for specific cysteine conjugation, Bioorganic & Medicinal Chemistry Letters, 2017, 27,3486-3489  DOI: 10.1016/j.bmcl.2017.05.069
    Tags: 王子田 A01
  4. Delsuc*. N.; Uchinomiya, S.; Ojida A.; Hamachi I, A host–guest system based on collagen-like triple-helix hybridization, Chemical Communications, 2017, 53, 6856-6859 
    DOI :10.1039/C7CC03055J
    Tags: 王子田 A01
  5. Shigemitsu, H.; Fujisaku, T.; Tanaka, W.; Kubota, R.; Minami, S.; Urayama, K.; Hamachi, I.*, An adaptive supramolecular hydrogel comprising self-sorting double nanofibre networks, Nature Nanotechnology, 2018, 13, 165-175 DOI:10.1038/s41565-017-0026-6
    Tags: 浜地 A01
  6. Ziadi, A.; Uchida, N.; Kato, H.; Hisamatsu, R.;Sato, A.; Hagihara, S.; Itami, K.; Torii, K.U., Discovery of Synthetic Small Molecules that Enhance the Number of Stomata: C-H Functionalization Chemistry for Plant Biology, Chem. Commun., 2017, 53, 9632-9635. DOI:10.1039/C7CC04526C
    Tag: 萩原 A01

  7. Amaike, K.; Tamura, T.; Hamachi*, I., Recognition-driven chemical labeling of endogenous proteins in multi-molecular crowding live cells, Chemical Communications, Feature Article, 2017, 53, 11972-11983 DOI: 10.1039/c7cc07177a.
    Tags: 浜地 A01

  8. Tamura, T.; Song, Z.; Amaike, K.; Lee, S.; Yin, S.; Kiyonaka, S.; Hamachi*, I., Affinity-guided Oxime Chemistry for Selective Protein Acylation in Live Tissue Systems, Journal of the American Chemical Society, 2017, 139(40), 14181-14191 DOI: 10.1021/jacs.7b07339.
    Tags: 浜地 A01

  9. Matsuo, K.; Nishikawa, Y.; Masuda, M.; Hamachi*, I., Live-cell Protein Sulfonylation Based on Proximity-driven N-Sulfonyl Pyridone Chemistry, Angewandte Chemie International Edition, 2018, 15, 659-662 DOI: 10.1002/anie.201707972.
    Tags: 浜地 A01

  10. Uchida, N.; Takahashi, K.; Iwasaki, R.; Yamada, R.; Yoshimura, M.; Endo, T. A. ; Kimura,S.; Zhang, H.; Nomoto, M.; Tada, Y.; Kinoshita, T.; Itami, K.; Hagihara, S.;  Torii, K. U., Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair, Nat. Chem. Biol., 2018, 14, 299-305, DOI: 10.1038/nchembio.2555.
    Tags: 萩原A01
  11. Yoshimura, M.; Sato, A.; Kuwata, K.; Inukai, Y.; Kinoshita, T.; Itami, K.; Tsuchiya, Y.; Hagihara, S., Discovery of shoot branching regulator targeting strigolactone re-ceptor DWARF14, ACS Central Science, Article ASAP, DOI: 10.1021/acscentsci.7b00554
    Tags: 萩原A01

  12. Ueda, T.; Tamura, T.; Hamachi, I., In situ Construction of Protein-based Semisynthetic Biosensors, ACS Sensors, 2018, 3 ( 3 ) 527 – 539  DOI :10.1021/acssensors.7b00894
    Tags: 浜地 A01

  13. Kiyonaka S.*; Sakamoto, S.; Wakayama, S.; Morikawa Y.; Tsujikawa M.; Hamachi I.*, Ligand-directed chemistry of AMPA receptors confers live-cell fluorescent biosensors, ACS Chemical Biology, Article ASAP, 2018, DOI : 10.1021/acschembio.7b01042
    Tags: 浜地 A01

  14. Takaoka, Y.; Uchinomiya, S.; Kobayashi, D.; Endo, M.; Hayashi, T.; Fukuyama, Y.; Hayasaka, H.; Miyasaka, M.; Ueda, T.; Shimada, I.; Hamachi, I., Endogenous Membrane Receptors Labeling by Reactive Cytokines/Growth Factors to Chase Their Dynamics in Live Cells, Chem, 2018, 4, 1451-1464 Doi.org/10.1016/j.chempr.2018.03.021
    Tags: 浜地 A01

  15. Hostachy, S.; Masuda, M.; Miki, T.; Hamachi, I.; Sagan, S.; Lequin, O.; Medjoubi, K.; Somogyi, A.; Delsuc*, N.; Policar* C., Graftable SCoMPIs Enable The Labeling and X-Ray Fluorescence Imaging of Proteins, Chemical Science, 2018, 9, 4483-4487 (2018) DOI:10.1039/c8sc00886h
    Tags: 浜地 A01

  16. Tamura, T.; Ueda, T.; Goto, T.; Tsukidate, T.; Shapira, Y.; Nishikawa, Y.; Fujisawa, A.; Hamachi*, I., Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide, Nature Communications, 2018, 9, 1870, DOI:10.1038/s41467-018-04343-0
    Tags: 浜地 A01

  17. Kubota, R.; Liu, S.; Shigemitsu, H.; Nakamura, K.; Tanaka, W.; Ikeda, M.; Hamachi, I., Imaging-Based Study on Control Factors over Self-Sorting of Supramolecular Nanofibers Formed from Peptide- and Lipid-Type Hydrogelators, Bioconjugate Chemistry, 2018, Just accepted. DOI:10.1021/acs.bioconjchem.8b00260
    Tags: 浜地 A01

  18. Matsumoto, G.; Inobe, T.; Amano, T.; Murai, K.; Nukina, N.; Mori, N., N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression, Scientific Reports, 2018, 8, 9585 DOI: 10.1038/s41598-018-27872-6
    Tags: 伊野部 A01

  19. Inobe, T.; Tsukamoto, M.; and Nozaki, M., Proteasome-mediated protein degradation is enhanced by fusion ubiquitin with unstructured degron. Biochem. Biophys. Res. Commun., 2018, 501, 948-954 DOI: 10.1016/j.bbrc.2018.05.088
    Tags: 伊野部 A01

  20. Yamatsugu, K.; Furuta, M.; Xi, S.; Amamoto, Y.; Liu, J.; Kawashima, S. A.; Kanai, M., Kinetic Analyses and Structure-Activity Relationship Studies of Synthetic Lysine Acetylation Catalysts, Bioorg. Med. Chem, 2018, In press
    Tags: 山次 A01

  21. Sato, S.; Hatano, K.; Tsushima, M.; Nakamura, H., 1-Methyl-4-aryl-urazole (MAUra) Labels Tyrosine in Proximity to Ruthenium Photocatalyst Chem. Commun. 2018, 54, 5871-5874. 
    DOI: 10.1016/j.bmc.2018.05.002
    Tags: 中村 A01

  22. Ueda, H.; Yoshimori, A.; Nakamura, H., Discovery of bicycle[3,3,1]non-2-ene as a novel skeleton for HIF-1 inhibitors, Bioorg. Med. Chem, 2018, In press. DOI: 10.1016/j.bmc.2018.05.002
    Tags: 中村 A01

  23. Yamada, R.; Murai, K.; Uchida, N.; Takahashi, K.; Iwasaki, R.; Tada, Y.; Kinoshita, T.; Itami, K.; Torii, U. K.; Hagihara, S., A super strong engineered auxin-TIR1 pair, Plant and Cell Physiology, in press, DOI:10.1093/pcp/pcy127
    Tags: 萩原 A01
  24. Fendrych, M.; Akhmanova, M.; Merrin, J.; Glanc, M.; Hagihara, S.; Takahashi, K.; Uchida, N.; Torii, U. K.; Friml, J., Rapid and reversible root growth inhibition by TIR1 auxin signalling, Nat. Plants., 2018, 4, 453-459. DOI: 10.1038/s41477-018-0190-1
    Tags: 萩原 A01
  25. Restu. W. K.; Nishida. Y.; Yamamoto. S.; Ishii. J.; Maruyama. T., Short oligopeptides for biocompatible and biodegradable supramolecular hydrogels. Langmuir, 2018, 34(27), 8065-80742. DOI: 10.1021/acs.langmuir.8b00362
    Tags: 丸山 A01
  26. Tainaka, K.; Murakami, T.C.; Susaki, E.A.; Shimizu, C.; Saito, R.; Takahashi, K.; Hayashi-Takagi, A.; Sekiya, H.; Arima, Y.; Nojima, S.; Ikemura, M.; Ushiku, T.; Shimizu, Y.; Murakami, M.; Tanaka, K.F.; Iino, M.; Kasai, H.; Sasaoka, T.; Kobayashi, K.; Miyazono, K.; Morii, E.; Isa, T.; Fukayama, M.; Kakita, A.; Ueda, H.R.
    Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents. Cell Reports, 2018, 24(8), 2196-2210.e9. DOI: 10.1016/j.celrep.2018.07.056.
    Tags: 田井中A01
  27. Zhu, H.; Tamura, T.; Hamachi, I., Chemical Proteomics for Subcellular Proteome Analysis, Curr. Opin. Chem. Biol., 2018, 48:1-7, DOI:10.1016/j.cbpa.2018.08.001.
    Tags: 浜地 A01
  28. Kubota, R.; Nomura, W.; Iwasaka, T.; Ojima, K.; Kiyonaka, S.; Hamachi, I., A Chemogenetic Approach Using Ni(II) Complex-Agonist Conjugates Allows to Selectively Activate Class A G Protein-Coupled Receptors, ACS Central Science, 2018,4 (9), pp 1211–1221. DOI:10.1021/acscentsci.8b00390
    Tags: 浜地 A01
  29. Sakagami, K.; Masada, T.; Kjawano, K.; Futaki, S., Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides. Mol. Pharm., 2018, 15, 1332-1340. DOI: 10.1021/acs.molpharmaceut.7b01130
    Tags: 二木A01
  30. Tainaka, K.; Murakami, T.C.; Susaki, E.A.; Shimizu, C.; Saito, R.; Takahashi, K.; Hayashi-Takagi, A.; Sekiya, H.; Arima, Y.; Nojima, S.; Ikemura, M.; Ushiku, T.; Shimizu, Y.; Murakami, M.; Tanaka, K.F.; Iino, M.; Kasai, H.; Sasaoka, T.; Kobayashi, K.; Miyazono, K.; Morii, E.; Isa, T.; Fukayama, M.; Kakita, A.; Ueda, H.R.
    Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents. Cell Reports, 2018, 24(8), 2196-2210.e9. DOI: 10.1016/j.celrep.2018.07.056.
    Tags: 田井中A01
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Original papers A01 Group

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